Category Archives: Pain-Relief

State-Level Policies May Reduce Disparities in Pain Prevalence

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PainRelief.com Interview with:
Rui Huang MA
Department of Sociology
University at Buffalo
Buffalo, NY

PainRelief.com: What is the background for this study?

Response: In the U.S., approximately 58.5 million people (23.7% of adults) have arthritis, and at least 15 million of them suffer from severe arthritis-attributable joint pain. Severe joint pain is strongly associated with impaired functioning, disability, mortality, and limited life chances. People with less education disproportionately suffer from joint pain and reduced quality of life.

However, existing research on social determinants of pain relies primarily on individual-level data; it rarely examines the role of macro sociopolitical contexts, such as state-level policies.  Moreover, relatively little is known about the geographic distribution of pain, and even less is known about geographic variation in socioeconomic disparities in pain. 

To our knowledge, this is the first study to look at how U.S. state-level policies and characteristics shape risk of pain, and educational disparities in pain.

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Study Finds Opioids No Better Than Placebo for Back or Neck Pain Relief

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PainRelief.com Interview with:
Christine Lin | Professor
The University of Sydney                                           
Sydney Musculoskeletal Heatlh
Faculty of Medicine and Health, Sydney School of Public Health
Institute for Musculoskeletal Health                             
Gadigal Country King George V Building
Royal Prince Alfred Hospital NSW Australia

PainRelief.com: What is the background for this study?

Response: Opioids are one of the most commonly prescribed pain medicines for low back pain and neck pain, but before this trial we did not have robust, direct evidence that they are effective for acute low back pain and neck pain.

PainRelief.com: What are the main findings?

Response: We found that taking opioids did not relieve acute low back pain and neck pain in the short term, and led to worse outcomes in the long term. We randomly assigned people with acute low back pain or neck pain to take opioids or placebo (identical tablets but with no active ingredients) for up to 6 weeks, in addition to getting the best advise on how to manage their pain from their doctor. We followed these people up for 1 year.

At 6 weeks, people in the opioid group did not report lower pain levels compared to people in the placebo group. Nor were there differences in pain outcomes at 2 and 4 weeks, or in other outcomes such as physical function, recovery time, or quality of life.

Surprisingly at 1 year, people who took opioids had slightly worse pain and an increased risk of opioid misuse.

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Racial Differences in Chronic Pain Among Football Players

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PainRelief.com Interview with:
Robert R Edwards, Ph.D.
Associate Professor of Anaesthesia
Pain Management Center
Brigham and Women’s Hospital

PainRelief.com: What is the background for this study?

Response: Chronic pain affects over 100 million American adults, and is a leading cause of reduced quality of life. However, in the US, the of burden of pain falls most heavily on members of racial and ethnic minority groups who frequently report more pervasive and severe pain compared with those in the majority.

In this study we evaluated race differences in pain among nearly 4,000 former professional American-style football players who self-identified as either Black or white.

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Leisure Time Exercise May Increase Pain Tolerance

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PainRelief.com Interview with:
Anders Pedersen Årnes
Department of Pain
University Hospital of North Norway in Tromsø

PainRelief.com: What is the background for this study?

exercise-pain-elderly

Response: The international association for the study of pain has actually deemed 2023 the global year for integrative pain care, which emphasizes non-drug, self-management care.

Exercise is an important way of managing chronic pain conditions, as there are few real pharmaceutical alternatives for treating them. Several studies point towards our ability to process pain signals as a possible contributing reason to chronic pain, as that often is seen to behave differently in those with chronic pain to those without. Since physical activity also appears to be a useful tool for preventing and treating chronic pain, we are trying to figure out whether this effect on pain sensitivity tolerance be one of the mechanisms through which physical activity protects against chronic pain.

This current study represents a first epidemiological look at how physical activity over time relates to pain tolerance over time in a whole population.

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COVID Effects on Nerves May Lead to Better Pain Relief Medications

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PainRelief.com Interview with:
Venetia Zachariou PhD
Edward Avedisian Professor
Chair of Pharmacology, Physiology & Biophysics
Boston University Chobanian & Avedisian School of Medicine

PainRelief.com: What is the background for this study?

Response: COVID-19, the disease resulting from SARS-CoV-2 infection, is associated with highly variable clinical outcomes that range from asymptomatic disease to death. For those with milder infections, COVID-19 can produce respiratory infection symptoms (cough, congestion, fever)  as well as loss of the sense of smell.

A substantial number of actively infected patients suffering from both mild and severe infections experience sensory-related symptoms, such as headache, visceral pain, Guillain-Barre syndrome (GBS), nerve pain and inflammation. In most patients these symptoms subside after the infection ends, but, for other patients, they can persist. 

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Patient Preferred Music Therapy Reduced Pain in Real World Settings

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PainRelief.com Interview with:
Seneca Block, Ph.D(c), MT-BC  
Board Certified Music Therapist and
The Lauren Rich Fine Endowed Director for Expressive Therapies
University Hospitals Connor Whole Health

PainRelief.com: What is the background for this study?

Response: University Hospitals Connor Whole Health has developed an extensive network of inpatient music therapy programs through out 8 major community medical centers across North Eastern Ohio. Music therapy is an evidence-based practice that was used through out these locations to provide front-line non pharmacological treatment of pain, stress and anxiety.

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JAMA Study Finds Clinicians Not Maximizing Opportunities to Initiate Buprenorphine Treatment For Patients With Opioid Addiction

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PainRelief.com Interview with:
Kao-Ping Chua, MD, PhD
Susan B. Meister Child Health Evaluation and Research Center
Department of Pediatrics, University of Michigan Medical School
Ann Arbor MI 48109

Kao-Ping Chua

PainRelief.com: What is the background for this study?

Response: Opioid overdose deaths are at a record high in the U.S. Many opioid overdose deaths can be prevented by medications for opioid use disorder, such as buprenorphine, a drug that can prescribed in office settings. However, buprenorphine cannot prevent opioid overdose deaths if patients are never started on the medication or only stay on the medication for a short time. For that reason, rates of buprenorphine initiation and retention are critical metrics for measuring how well the U.S. health care system is responding to the opioid epidemic.

At the time we started our study, several other research groups had evaluated U.S. rates of buprenorphine initiation and retention using data through 2020. However, more recent national data were lacking. We felt that this was an important knowledge gap given the many changes in society that have occurred since 2020. For example, it was possible that the relaxation of social distancing measures during 2021 and 2022 might have reduced barriers to health care visits, thereby increasing opportunities to initiate treatment for opioid addiction with buprenorphine.

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EVALI – Vaping and Lung Injury – Storylines on Popular Medical Dramas May Change Behavior

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PainRelief.com Interview with:
Beth Hoffman, PhD, MPH (she/her)
Postdoctoral Associate
Center for Social Dynamics and Community Health
Department of Behavioral and Community Health Sciences
University of Pittsburgh School of Public Health

PainRelief.com: What is the background for this study?

Response: Previous studies suggested that hearing about EVALI in the news might stop people from vaping or get them to quit, but there had yet to be research examining if storylines on fictional medical television shows could have the same effects. There had also been few studies to date leveraging Twitter data, which allowed us to see how viewers were reacting to the storylines in real-time, in their organic viewing environment.

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Study Finds Uncertain Effectiveness of Common Medications for Low Back Pain Relief

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PainRelief.com Interview with:

Dr. Wewege

Dr Michael Wewege, PhD
Research Fellow – Neuroscience Research Australia

Prof. McAuley

Prof James McAuley, PhD
Director – Centre for Pain IMPACT, Neuroscience Research Australia,
Professor – School of Health Sciences,
University of New South Wales
Sydney, Australia




PainRelief.com: What is the background for this study?

Response: We conducted this study because medicines are the most common treatment for adults with acute non-specific low back pain. One of the most important questions is “What is the best medicine to use?” We wanted to compare the medicines with each other because this is the information patients and physicians want to know, but previous research has focused on only comparing medicines to placebo. Physicians are deciding between these medicines based on their clinical expertise; we hoped to support their decision making with a rigorous piece of research.

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Study Evaluates Equine-Facilitated Therapy For Back Pain Relief

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PainRelief.com Interview with:
Sanna Mattila-Rautiainen
Biomedicine, Sports and Exercise Medicine
University of Eastern Finland

PainRelief.com: What is the background for this study?

Response: The background of our study is to evaluate the effect of 12 weeks Equine Facilitated Physical therapy intervention for Chronic Low Back Pain patients´ functional impairments that were self-assessed, to their wellbeing and amount of pain.

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