Genetics Matter In Risk of Opioid Addiction

Dr. Curry from the Mayo Clinic discusses how genetics influence how the body processes and reacts to medications.  Excepts are from the meeting sponsored by the Mayo Clinic in October 2017 : IIndividualizing Medicine 2017: Advancing Care Through Genomics,  a two day conference hosted by the Mayo Clinic Center for Individualized Medicine.

New Technique Can Help Pinpoint Where Heroin Batches Come From

New method describes measuring  strontium isotopes can be used as a chemical marker for geography and geology to differentiate heroin samples from different geographic regions.

Joshua DeBord, Ali Pourmand, Sarah C. Jantzi, Sini Panicker, Jose Almirall. Profiling of heroin and assignment of provenance by 87 Sr/ 86 Sr isotope ratio analysis. Inorganica Chimica Acta, 2017; DOI: 10.1016/j.ica.2017.07.049

FDA To Require Opioid Manufacturers To Train Health Care Providers

The FDA “notified 74 manufacturers of immediate-release opioid analgesics intended for use in the outpatient setting that their drugs will now be subject to a more stringent set of requirements under a Risk Evaluation and Mitigation Strategy (REMS).

The REMS requires that training be made available to health care providers who prescribe IR opioids, including training on safe prescribing practices and consideration of non-opioid alternatives.”

FDA Takes Important Steps to Stem the Tide of Opioid Misuse and Abuse

Study Reviews Imitrex Nasal Spray (sumatriptan) for Migraine Pain Relief

This study is systematic review and meta-analysis to evaluate the tolerability and efficacy of intranasal sumatriptan for the treatment of acute migraine attacks.  Taste disturbance was a leading side effect.

Intranasal sumatriptan for acute migraine attacks: a systematic review and meta-analysis.

Menshawy A1,2,3, Ahmed H2,4,5, Ismail A1,2,6, Abushouk AI7,8,9, Ghanem E1,2, Pallanti R1,10, Negida A2,4,5.
Note: Content is Not intended as medical advice. Please consult your health care provider regarding your specific medical condition and questions.

Emergency Rooms Using Shorter, Lower Doses of Opioids

A recent study from the Annals of Emergency Medicine founds that compared to other settings, emergency room prescriptions for opioids found more likely to be in compliance with CDC recommendations and have a lower risk of progression to long term opioid use.

Cardiovascular Risk of NSAIDS for Pain Relief

Patompong Ungprasert, MD, MS  of the Mayo Clinic reviews the cardiovascular risk of NSAIDS used for pain relief, including arthritis.

CVS To Limit Opioid Prescriptions To 7 Days For New Patients

As part of CVS’s commitment to fighting the national opioid abuse epidemic, CVS is:

  •  limiting to seven days the supply of opioids dispensed for certain acute prescriptions for patients who are new to therapy;
  • limiting the daily dosage of opioids dispensed based on the strength of the opioid; and
  • requiring the use of immediate-release formulations of opioids before extended-release opioids are dispensed.

Chronic Pain As A Global Health Issue

This authors suggest that chronic pain should be considered a global health priority as 1 in 5 people suffer from some form of long term pain. Arthritis, nerve damage, and cancer pain are the leading causes of chronic pain.

Pain as a global public health priority

  • Daniel S Goldberg and Summer J McGee
BMC Public Health201111:770