Rutgers Study Evaluates Telehealth Delivered Mindfulness Therapy in OUD Patients with Chronic Pain Interview with:
Nina A. Cooperman, PsyD
Department of Psychiatry
Division of Addiction Psychiatry
Rutgers Robert Wood Johnson Medical School
Piscataway, New Jersey

Dr Nina Cooperman, Photo by John O’Boyle What is the background for this study?

Response: This study aimed to evaluate the impact of a novel intervention, Mindfulness Oriented Recovery Enhancement (MORE), on opioid use and chronic pain among individuals receiving methadone treatment (MT).

The main goal of this study was to conduct a clinical trial to assess online MORE, delivered remotely, through secure video or phone conferencing, with respect to a range of clinical outcomes.

This study will involve a 2-arm individually randomized controlled trial design that compares MORE and treatment as usual (TAU). What are the main findings?

Response: In this randomized clinical trial of 154 individuals with chronic pain in methadone treatment for an opioid use disorder, relative to usual care, MORE plus usual care demonstrated efficacy for decreasing drug use, pain, and depression and increasing methadone treatment retention and adherence. What should readers take away from your report?

Response: The development of implementation strategies to train clinicians and to integrate MORE into treatment programs is needed to disseminate this potentially impactful intervention to those with OUD and chronic pain. What recommendations do you have for future research as a result of this study?

Response: Phase 3 clinical trials that compare MORE with other interventions are warranted. Is there anything else you would like to add? Any disclosures?

Response: Dr Cooperman reported receiving grants from the National Institutes of Health and Arnold Ventures during the conduct of the study. Drs Hanley and Garland reported receiving grants from the National Center for Complementary and Integrative Health and the National Institute on Drug Abuse during the conduct of this study. Dr Garland reported receiving personal fees from training clinicians in mindfulness; being director of the Center on Mindfulness and Integrative Health Intervention Development; receiving honoraria and payment for delivering seminars, lectures, and teaching engagements (related to training clinicians in Mindfulness-Oriented Recovery Enhancement [MORE]), including those sponsored by institutions of higher education, government agencies, academic teaching hospitals, and medical centers; receiving royalties from the sale of books related to MORE; and being a licensor to BehaVR, LLC. No other disclosures were reported.


Cooperman NA, Lu S, Hanley AW, et al. Telehealth Mindfulness-Oriented Recovery Enhancement vs Usual Care in Individuals With Opioid Use Disorder and Pain: A Randomized Clinical Trial. JAMA Psychiatry. Published online December 07, 2023. doi:10.1001/jamapsychiatry.2023.5138

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Last Updated on December 16, 2023 by