Early Physical Therapy Can Be Protective Against Chronic Opioid Use

PainRelief.com Interview with:

Steven Z. George, PT, PhD  Professor Director of Musculoskeletal Research Duke Clinical Research Institute Vice Chair of Clinical Research Orthopaedic Surgery

Dr. George

Steven Z. George, PT, PhD 
Professor
Director of Musculoskeletal Research
Duke Clinical Research Institute
Vice Chair of Clinical Research
Orthopaedic Surgery

PainRelief.com: What is the background for this study? What are the main findings?Response: This study adds to existing health services research investigating the sequence of services/providers for musculoskeletal pain and its impact on opioid use.

The study suggest that early physical therapy (PT) for the 4 most common musculoskeletal conditions (back, neck, shoulder, and knee) can be protective of chronic/long term opioid use for individuals that were opioid naïve when presenting for their care.  What is different about this study is that the 4 conditions were studied in the same cohort and the same definition of early PT was used (many of the previous studies just looked at 1 conditions, and used different definitions of early physical therapy).  The other thing that was different is that we used a larger dataset of private insurance providers, so this study cuts across different regions of the study (many of the previous studies included one health system).

There was notable consistency in the findings for the 4 conditions and protection of any opioid use, but there were some contingencies.

First was that there was no benefit on decreased dosage for individuals with neck pain – as that was not expected.

Second was that in a follow up sensitivity analysis it looked like the largest benefit of early physical therapy may be for those with back and knee pain.  Continue reading

Three Genes Linked To Chronic Back Pain

PainRelief.com Interview with:
"Back Pain" by betterhealthosteopathy is licensed under CC PDM 3.0cDr. Frances MK Williams PhD

Department of Twin Research and Genetic Epidemiology
Division of Genetics & Molecular Medicine
Reader, King’s College London
Honorary Consultant in Rheumatology
Guy’s and St Thomas’ NHS Foundation Trust

PainRelief.com: What is the background for this study?

Response: This study was led by scientists at King’s College London and the University of Washington. It has identified three new genes associated with the development of chronic back pain.

The findings, which are published in PLOS Genetics, could pave the way for the creation of more effective treatments for the condition, the leading cause of disability worldwide.

Part funded by the European Union, the research project focussed on understanding why in most people an episode of back pain gets better, while in around 20% of people it can persist for many months – chronic back pain is defined as pain that persists for more than three months.

To better understand the origins of the chronic condition, researchers conducted a genome-wide association meta-analysis (GWAS) of chronic back pain studies comprising a total of 440,000 individuals. The average age of the study’s participants ranged from 50 to 76 years, and the genders were approximately balanced.  Continue reading