PainRelief.com Interview with: Dr. Daniel Whibley PhD Department of Physical Medicine and Rehabilitation University of Michigan, Ann Arbor, Michigan Epidemiology Group, School of Medicine, Medical Sciences and Nutrition University of Aberdeen, Scotland, UK
PainRelief.com: What is the
background for this study? What are the
Response: Older adults with osteoarthritis commonly report symptoms of pain, fatigue and poor sleep quality. Previous research has investigated how this symptoms are cross-sectionally and longitudinally associated with each other. However, no previous studies have investigated how the quality of a night’s sleep impacts on the next day’s course of pain and fatigue in this clinical population.
We found that poor sleep quality was associated with greater pain intensity and fatigue on awakening when compared to a good night’s sleep and that, over the course of the day, the effects were sustained. Although a night of better quality sleep was associated with less pain and fatigue on awakening, these symptoms worsened more rapidly throughout the day, such that as the day progressed the effect of the previous night’s sleep became less and less important.
Dawn C. Buse PhD Clinical Professor of Neurology Albert Einstein College of Medicine New York City
PainRelief.com: What is the
background for this study?
Response: Sleep is essential in the regulation of a wide range of homeostatic
functions. Dysregulation of sleep process may be triggers for
migraine attacks and increase the risk of migraine disease
chronification. Migraine is comorbid with a range of medical,
neurologic, and psychiatric comorbidities that may exacerbate the disease,
complicate treatment, and reduce health-related quality of
life. These comorbidities include sleep disorders such as sleep
apnea, insomnia, circadian rhythm (i.e., sleep-wake) disorders, and sleep
The Chronic Migraine Epidemiology and Outcomes
(CaMEO) Study is a longitudinal study that used a series of web-based surveys
over 15 months to assess migraine symptoms, burden and patterns of healthcare
utilization among people in the US population. Validated
questionnaires were used to assess many comorbidities. Migraine can
be classified based on the number of headache days per month into episodic
migraine (<15 headache days/month) and chronic migraine (≥15 headache
In this cross-sectional analysis of data from the Chronic Migraine Epidemiology and Outcomes (CaMEO) Study, we assessed sleep apnea and poor sleep quality in a US population based sample of 12,810 people with migraine. Respondents were stratified by episodic (11,699) and chronic (1,111) migraine and by body mass index (BMI).
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