Caesarean section associated with higher odds of sleep disorder after delivery

PainRelief.com Interview with:
Moe Takenoshita, M.B.B.Ch.
Postdoctoral scholar, Stanford University

PainRelief.com: What is the background for this study?

Response: Sleep is a key component of postpartum recovery.1 It is linked to maternal mental, physical and social wellbeing, as well as maternal-infant bonding and infant outcomes.2–5 Several factors have been associated with impaired postpartum sleep, including maternal and infant clinical factors, socioeconomic and environmental factors.6,7 However, few studies have looked at the impact of delivery mode on postpartum sleep. This is significant because 32% of deliveries in the United States are caesarean delivery, and caesarean delivery rates are rising globally.8

We designed this study to look at how postpartum sleep experiences and the incidence of sleep disorders differ between caesarean and vaginal delivery. We also aimed to explore the relationship between delivery mode, pain and sleep.

Swedish Study Examines Risks of ASD/ADHD After Prescribed Opioids During Pregnancy

PainRelief.com Interview with:

Emma N. Cleary (she/her)
Clinical Psychology PhD Candidate
Developmental Psychopathology Lab
Indiana University Bloomington

PainRelief.com: What is the background for this study?

Response: Pain is common during pregnancy and one of the options for managing it is with prescribed opioid pain medications. When pregnant patients and their physicians try to make decisions about using these medications, there are often concerns about impacts on fetal development given that these medications cross the placenta.

Previous studies have identified associations between prenatal exposure to opioids pain medications and increased risk of neurodevelopmental disorders like autism spectrum disorder (ASD) and  attention-deficit/hyperactivity disorder (ADHD), but it is unclear whether this is causal.

ICAHN Mount Sinai Analysis Suggests Women Should Be Careful About Using Acetaminophen During Pregnancy

PainRelief.com Interview with:
Diddier Prada, MD, Ph.D. 
Assistant Professor 
Institute for Health Equity Research
Department of Population Health Science and Policy 
Department of Environmental Medicine
Icahn School of Medicine at Mount Sinai 
New York City, NY, USA
https://scholars.mssm.edu/en/persons/diddier-prada

PainRelief.com: What is the background for this study?

Response: Earlier research has indicated that using acetaminophen (such as Tylenol) during pregnancy might increase the likelihood of children developing neurodevelopmental conditions like autism or ADHD.

Data shows that more than half of pregnant women rely on acetaminophen in some regions. Various well-conducted studies, including long-term group observations and case-comparison analyses, have identified a potential association, though some found no relationship, and a few even hinted at a possible protective effect. However, these studies often faced challenges, such as depending on mothers’ memory for usage data, failing to consider underlying reasons for taking the drug (e.g., illness or fever), or employing inconsistent approaches, which complicates drawing firm conclusions. By applying a transparent and consistent framework, the Navigation Guide methodology, to assess the studies’ quality, credibility, and evidence strength, we aimed to offer a more reliable overview than previous reviews.

CAMH Study Finds Potential Risks to Baby from Cannabis Exposure During Pregnancy

PainRelief.com Interview with:
Maryam Sorkhou
PhD student at the Institute of Medical Sciences
University of Toronto

PainRelief.com: What is the background for this study?

Response: While studies on animals strongly suggest that exposure to cannabis during pregnancy can affect brain development, the impact of using cannabis during pregnancy in humans is not yet clear. Some studies suggest potential negative effects, while others find no impairments.

In light of increasing trends towards legalization and potentially decreased perceptions about the risks of cannabis, our meta-analysis of 57 studies aimed to fill this gap by exploring the associations between prenatal cannabis use and birth and childhood outcomes.