Are Off-Label Gabapentinoids Useful for Post-Operative Pain Relief? What should readers take away from your report?

Response: We observed no clinically meaningful analgesic effect for the perioperative use of gabapentinoids and an increased risk of adverse events. Our results do not support the routine use of gabapentin or pregabalin for the management of postoperative pain in adult patients. What recommendations do you have for future research as a result of this work?

Response: Based on the results of our trial sequential analysis, additional trials evaluating the effect gabapentinoids on postoperative acute pain intensity are not further required.

Nothing to disclose.


October 20, 2019
10/20/2019 7:45:00 AM – 10/20/2019 9:15:00 AM
Room W312AB
Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain:a Systematic Review and Meta-analysis
Michael Verret, M.D., François Lauzier, M.D., M.S., Ryan Zarychanski, M.D., M.S., Caroline Perron, M.S., Xavier Savard, M.D., Anne-marie Pinard, M.D., Guillaume Leblanc, M.D., Marie-Joelle Cossi, Ph.D., Alexis F. Turgeon, M.D., M.S.
Centre de recherche du CHU de Québec-Université Laval, Québec, Quebec , Canada


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